NEJM April 13, 2021
By Rachel Pryor, RN, MPH, Kaila Cooper, RN, MSN, CIC, Amy Britton, RN, MSN, Nikki Meador, MBA, Michelle Doll, MD, MPH, Emily J. Godbout, DO, MPH, Michael P. Stevens, MD, MPH, Arthur L. Kellermann, MD, MPH & Gonzalo Bearman, MD, MPH

Virginia Commonwealth University Medical Center’s implementation of aggressive, bundled multilevel infection prevention measures resulted in a tenfold decrease in SARS-CoV-2 transmission in the health care setting.


Although Virginia Commonwealth University Medical Center (VCUMC) minimized health care worker infections and exposures through the first and second waves of Covid-19, the arrival of the much larger third wave of Covid-19 sparked a substantial surge in cases. The third wave peaked among health care workers during the week of December 13, 2020, with 1% of the workforce (134 of 13,346 workers) testing positive for Covid-19. VCUMC implemented a bundle of intensified infection-control measures, augmented soon thereafter with the...

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